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Some patients experience persistent nausea, constipation, or gastrointestinal discomfort on tirzepatide that doesn't resolve with continued use or dose adjustments
GLP-1 does several things for your body, but when it comes to weight loss, its main job is to communicate with your body that you have consumed food
Nevertheless, although the number of patients who had a TyG index value of 8.8 (non-insulin resistance) increased significantly in both the no/low CKD risk and CKD groups after 12 months of treatment ( Figures 3A, B ), when further stratification according to CKD severity was performed, a lower proportion of patients achieving a TyG value 8.8 was reported in the subgroup of very high CKD risk ( Figures 3CE )
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